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Cancer, Alzheimer’s & Protein Origami

David Pincus | TEDxBeaconStreet

The two diseases most likely to afflict us as we age – cancer and neurodegenerative diseases like Alzheimer’s – may both have an Achilles’ heel. David Pincus will argue that the two are fundamentally linked by the vital cellular process of “protein folding”. This provocative talk posits that protein folding is the key to unlocking all cancers – not just for treating specific cancers, like breast cancer or lung cancer – and for all neurodegenerative diseases like Alzheimer’s, Parkinson’s and ALS.

David Pincus, a Fellow at the Whitehead Institute and recipient of the NIH Director’s Early Independence Award, is a molecular and cell biologist given the rare opportunity to direct an independent research laboratory and pursue his scientific ideas immediately following completion of his PhD. His studies on how cells respond to stress point to an underlying connection between cancer and neurodegenerative diseases that he hopes to exploit through research to potentially solve both.